Demonstration of the cancer cell antiproliferative strategy by using m6A demethylase ALKBH5 inhibitors 


We reported the antiproliferative effects of new ALKBH5 inhibitors on selected target cancer cell lines. In the case of leukemia cells proliferation was suppressed at low micromolar concentrations of inhibitors. The results obtained demonstrate the potential of ALKBH5 inhibition as a cancer-cell-type-selective antiproliferative strategy. 

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